Retrograde jejunal intussusception in one year old cat after treatment with metoclopramide and menbutone

Barbara Lukanc, Estera Pogorevc, Andreja Kastelic, Vladimira Erjavec


Intussusception refers to invagination or prolapse of one portion of the intestine into the part of the tract that either precedes or follows it. Young cats may be more likely to have idiopathic intussusception, and older cats with intussusception may be more likely to have primary gastrointestinal tract disease, i.e. neoplasia. An intussusception will result in either a partial or complete intestinal obstruction and this will lead to a variety of clinical signs depending on the chronicity, size and location of the intussusceptions.
In the literature no suggestion has been made to show association between intussusception and prokinetic or choleretic drug. A one year old male Maine Coon cat was presented with a history of anorexia, depression and inability to defecate for few days. On two consecutive days the cat was treated with metoclopramide, ranitidine, hyoscine butylbromide and menbutone. On the same day of therapy vomiting started and continued for three days before the moribund cat was presented to the clinic. In transverse ultrasonographic view, a target-like mass with multiple concentric hypo- and hyperechoic rings consistent with intussusception was seen in the left mesogastrium.
This paper describes that possible cause of intussusception may be iatrogenic by application of prokinetic metoclopramide and choleretic menbutone given to an obstipated cat.

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