• Bangyuan Wu Key Lab of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, 1-5 Beichenxi Road, Chaoyang, Beijing 100101; Key Laboratory of Southwest China Wildlife Resources Conservation (Ministry of Education), Nanchong, Sichuan 637009; College of Life Science, China West Normal University, Nanchong, Sichuan 637009 China
  • Juan Wang College of Life Science, China West Normal University, Nanchong, 637009 Sichuan, China
  • Tong Cai College of Life Science, China West Normal University, Nanchong, 637009 Sichuan, China
  • Chengdong Wang Key-laboratory of Endangered Animal Reproduction and Conservation and Genetics, China Conservation and Research Center for the Giant Panda, Wolong, 623006 Sichuan, China
  • Desheng Li Key-laboratory of Endangered Animal Reproduction and Conservation and Genetics, China Conservation and Research Center for the Giant Panda, Wolong, 623006 Sichuan, China
  • Linhua Deng Key-laboratory of Endangered Animal Reproduction and Conservation and Genetics, China Conservation and Research Center for the Giant Panda, Wolong, 623006 Sichuan, China
  • Xi Peng College of pharmacy, Chengdu University, Chengdu, 730000 Sichuan, China, Corresponding author, E-mail:



aged, giant panda, multiple organ dysfunction, pathology


The giant panda (Ailuropoda melanoleuca) is one of the most endangered species in the world. Climate change and susceptibility to disease are two of the greatest threats to this species. We performed a necropsy and histopathological exami- nation of the organs of an old panda and investigated the pathogenesis associated with death. Necropsy and histopathological observation revealed some typical age-related lesions, such as cataract, atherosclerosis, renal insufficiency and splenic atrophy. We also confirmed hepatic lesions associated with parasitic infection. Overall, our observations revealed that the predominant cause of mortality in this panda was multiple organ dysfunction (MOD).


Izvleček: Veliki panda (Ailuropoda melanoleuca) je ena najbolj ogroženih vrst na svetu. Vrsto najbolj ogrožajo podnebne spre- membe in dovzetnost za bolezni. Opravili smo nekropsijo in histopatološki pregled organov starega pande ter raziskali patoge- nezo, povezano s smrtjo. Z nekropsijo in histopatološkim opazovanjem smo odkrili nekatere značilne starostne spremembe, kot so katarakta, ateroskleroza, ledvična insuficienca in atrofija vranice. Potrdili smo tudi jetrne spremembe, povezane s parazitsko okužbo. Naša opažanja so pokazala, da je bil prevladujoči vzrok smrti tega pande disfunkcija več organov (MOD).

Ključne besede: star; veliki panda; disfunkcija več organov; patologija


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